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Beitragstitel Central vein occlusion after SARS-CoV-2 infection
Beitragscode P40
Autor:innen
  1. Aja Reinhold Präsentierende:r
  2. Gerald Stiegler Klinik Bellavista AG
  3. Christian Prünte Universitätsspital Basel
  4. Peter Meyer Augenklinik Universitätsspital Basel
Präsentationsform ePoster
Themengebiete
  • Retina Vitreous
Abstract-Text It is already known that in the context of a SARS-CoV-2 infection micro thrombi can occur in small capillary vessels. Post-mortem in particular, thrombi have been found in the choriocapillaris. Clinically, there is probably also an association between central vein occlusion and SARS-CoV-2 infection. In the present case, retinal central venous occlusion was described in a patient with COVID infection. The 37 year old patient was treated in the “Bella Vista Clinic” in Speicher. Therapy with Bevacicumab (Avastin, Roche) and Papaverine (Paveron, LINDEN) intravenous with parabulbar injections of Betamethason was initiated. Even if this is not the guideline-based therapy for macular edema in central venous occlusion, complete visual rehabilitation occurred. In accordance with the previous observations of microthombi in choroidal vessels of patients who died of COVID, a thrombotic event in the venous system of the optic disc region can be assumed as the cause. Furthermore, it has been shown that endothelial cells affected by the virus can be edematous thickened constricting the vessel lumen. Vascular inflammation was probably successfully treated with the retrobulbar steroid injections. It is also possible that the systemic effect of Papaverine on vascular smooth muscle (relaxation) has a positive effect. Both the exact mechanism of central retinal vein thrombosis and its therapeutic possibilities remain speculative and need to be investigated in larger case series.